{"id":10872,"date":"2015-07-02T00:25:19","date_gmt":"2015-07-02T04:25:19","guid":{"rendered":"http:\/\/hobbyspace.com\/Blog\/?p=10872"},"modified":"2015-07-02T00:25:19","modified_gmt":"2015-07-02T04:25:19","slug":"video-growing-better-protein-crystals-in-microgravity","status":"publish","type":"post","link":"https:\/\/hobbyspace.com\/Blog\/?p=10872","title":{"rendered":"Video: Growing better protein crystals in microgravity"},"content":{"rendered":"<p>Below is\u00a0a NASA video and article about protein growth in microgravity. (Note that a Schering Plough\u00a0protein crystal experiment carried out on Shuttle Columbia&#8217;s last flight\u00a0led directly to a treatment for Hepatitis-C:\u00a0<a href=\"http:\/\/spaceksc.blogspot.com\/2013\/07\/im-doctor-not-astronaut.html\" target=\"_d\">Space KSC: I&#8217;m a Doctor, Not an Astronaut &#8211; Space KSC<\/a>) :<\/p>\n<p style=\"text-align: center;\"><strong><a href=\"http:\/\/www.nasa.gov\/mission_pages\/station\/research\/news\/crystals\" target=\"_d\">ISS Benefits For Humanity: Hope Crystallizes<\/a><\/strong><\/p>\n<p>In one of many direct Earth applications of<strong> <a href=\"http:\/\/www.nasa.gov\/mission_pages\/station\/research\/index.html#.U_y7T_mwLMo\">International Space Station<\/a><\/strong> research, the newest<strong>\u00a0<a href=\"http:\/\/www.nasa.gov\/mission_pages\/station\/research\/benefits\/index.html#.U_zPavmwLMo\">Benefits for Humanity<\/a><\/strong> video in the<strong> <a href=\"http:\/\/www.nasa.gov\/mission_pages\/station\/research\/videos\/index.html\">Benefits series<\/a>\u00a0<\/strong>highlights how high-quality crystals grown in microgravity lead to new therapeutics for disease. Learn how the investigation of protein crystals in space is helping to treat Duchenne Muscular Dystrophy (DMD), an incurable genetic disorder affecting the muscles with onset usually in early childhood and primarily in young males.<\/p>\n<p><span class=\"embed-youtube\" style=\"text-align:center; display: block;\"><iframe loading=\"lazy\" class=\"youtube-player\" width=\"1600\" height=\"900\" src=\"https:\/\/www.youtube.com\/embed\/1jEx4Q_nBW8?version=3&#038;rel=1&#038;showsearch=0&#038;showinfo=1&#038;iv_load_policy=1&#038;fs=1&#038;hl=en&#038;autohide=2&#038;wmode=transparent\" allowfullscreen=\"true\" style=\"border:0;\" sandbox=\"allow-scripts allow-same-origin allow-popups allow-presentation allow-popups-to-escape-sandbox\"><\/iframe><\/span><\/p>\n<p>Research into a disease like DMD involves the study of the structure of associated proteins by crystallization, which helps researchers better understand protein function. This comprises making millions of copies of that protein and arranging them in three-dimensional rows. Crystals grown on Earth are impacted by gravity, which may affect the way the molecules align on the surface of the crystal. Researchers have discovered that growing crystals aboard the space station allows for slower growth and higher quality crystals.<\/p>\n<p><a href=\"http:\/\/www.nasa.gov\/sites\/default\/files\/thumbnails\/image\/earth-microgravity_0.jpg\" target=\"_blank\"><img loading=\"lazy\" decoding=\"async\" data-attachment-id=\"10873\" data-permalink=\"https:\/\/hobbyspace.com\/Blog\/?attachment_id=10873\" data-orig-file=\"https:\/\/hobbyspace.com\/Blog\/wp-content\/uploads\/2015\/07\/earth-microgravity_01.jpg\" data-orig-size=\"1510,860\" data-comments-opened=\"1\" data-image-meta=\"{&quot;aperture&quot;:&quot;0&quot;,&quot;credit&quot;:&quot;&quot;,&quot;camera&quot;:&quot;&quot;,&quot;caption&quot;:&quot;&quot;,&quot;created_timestamp&quot;:&quot;0&quot;,&quot;copyright&quot;:&quot;&quot;,&quot;focal_length&quot;:&quot;0&quot;,&quot;iso&quot;:&quot;0&quot;,&quot;shutter_speed&quot;:&quot;0&quot;,&quot;title&quot;:&quot;&quot;,&quot;orientation&quot;:&quot;1&quot;}\" data-image-title=\"earth-microgravity_0[1]\" data-image-description=\"\" data-image-caption=\"\" data-large-file=\"https:\/\/hobbyspace.com\/Blog\/wp-content\/uploads\/2015\/07\/earth-microgravity_01-1024x583.jpg\" class=\"aligncenter size-large wp-image-10873\" src=\"http:\/\/hobbyspace.com\/Blog\/wp-content\/uploads\/2015\/07\/earth-microgravity_01-1024x583.jpg\" alt=\"earth-microgravity_0[1]\" width=\"520\" height=\"296\" srcset=\"https:\/\/hobbyspace.com\/Blog\/wp-content\/uploads\/2015\/07\/earth-microgravity_01-1024x583.jpg 1024w, https:\/\/hobbyspace.com\/Blog\/wp-content\/uploads\/2015\/07\/earth-microgravity_01-300x171.jpg 300w, https:\/\/hobbyspace.com\/Blog\/wp-content\/uploads\/2015\/07\/earth-microgravity_01.jpg 1510w\" sizes=\"auto, (max-width: 520px) 100vw, 520px\" \/><\/a><\/p>\n<p>&nbsp;<\/p>\n<div class=\"caption\" style=\"padding-left: 30px;\"><em>In microgravity, crystals grow more slowly, but the molecules have time to more perfectly align on the surface of the crystal which returns much better research data.\u00a0Credits: NASA<\/em><\/div>\n<p>Since 2003, scientists with the <strong><a href=\"http:\/\/global.jaxa.jp\/\">Japan Aerospace Exploration Agency<\/a><\/strong> have conducted protein crystal growth investigations on the space station, including proteins associated with DMD. Having a better understanding of the protein\u2019s shape enabled researchers to design a drug that fits specifically into a location on the protein associated with DMD. The research team estimates that the drug may be able to slow the progression of DMD by half.<\/p>\n<p>\u201cStudying this protein led to a huge discovery,\u201d said Dr. Yoshihiro Urade, Ph.D., professor at the University of Tsukuba in Tsukuba, Japan. \u201cWhat we\u2019re talking about is potentially doubling the lifespan of many DMD patients, and it\u2019s all because of research opportunities afforded to us by the International Space Station.\u201d<\/p>\n<p>With many other protein crystal growth studies occurring or planned aboard the space station, many thousands of other proteins\u2019 structures could be determined. This is yet another way the orbiting laboratory is enabling research Off the Earth, For the Earth<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Below is\u00a0a NASA video and article about protein growth in microgravity. (Note that a Schering Plough\u00a0protein crystal experiment carried out on Shuttle Columbia&#8217;s last flight\u00a0led directly to a treatment for Hepatitis-C:\u00a0Space KSC: I&#8217;m a Doctor, Not an Astronaut &#8211; Space KSC) : ISS Benefits For Humanity: Hope Crystallizes In one of many direct Earth applications &hellip; <a href=\"https:\/\/hobbyspace.com\/Blog\/?p=10872\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">Video: Growing better protein crystals in microgravity<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[17,95,9],"tags":[],"class_list":["post-10872","post","type-post","status-publish","format-standard","hentry","category-living-in-space","category-micro-g-rd","category-science-and-technology"],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p34aWK-2Pm","jetpack-related-posts":[{"id":25193,"url":"https:\/\/hobbyspace.com\/Blog\/?p=25193","url_meta":{"origin":10872,"position":0},"title":"Redwire makes first sale of space-manufactured optical crystal","author":"TopSpacer","date":"July 6, 2022","format":false,"excerpt":"Seems like the announcement shown below from Redwire Space of a commercial sale of optical crystal made in microgravity should be getting more attention. It will definitely provide some encouragement to the many companies building crewed and uncrewed orbital platforms for which space manufacturing is a key target market. Only\u2026","rel":"","context":"In &quot;In Space Infrastructure&quot;","block_context":{"text":"In Space Infrastructure","link":"https:\/\/hobbyspace.com\/Blog\/?cat=15"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/hobbyspace.com\/Blog\/wp-content\/uploads\/2022\/07\/RWPayload-3-800x533-1-500x333.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":15166,"url":"https:\/\/hobbyspace.com\/Blog\/?p=15166","url_meta":{"origin":10872,"position":1},"title":"Kickstarter for STEM program with experiments for students to compare with results on ISS","author":"TopSpacer","date":"November 9, 2017","format":false,"excerpt":"A Kickstarter has opened to back a program to let students run crystal and microbe growing experiments on the ground to compare with similar experiments on the International Space Station: Kickstarter for STEM Education Program in Space Announced Xtronaut, NanoRacks, and DreamUp are launching two experiments to the International Space\u2026","rel":"","context":"In &quot;Education&quot;","block_context":{"text":"Education","link":"https:\/\/hobbyspace.com\/Blog\/?cat=22"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/hobbyspace.com\/Blog\/wp-content\/uploads\/2017\/11\/5b1f71ea2e90f653236aba646473f754_original1.jpg?resize=350%2C200","width":350,"height":200},"classes":[]},{"id":6498,"url":"https:\/\/hobbyspace.com\/Blog\/?p=6498","url_meta":{"origin":10872,"position":2},"title":"Space policy roundup &#8211; Feb.15.14","author":"TopSpacer","date":"February 15, 2014","format":false,"excerpt":"More space policy\/politics related posts: Buzz Aldrin: Space policy, cooperative efforts to Mars and the need to inspire future generations - Soapbox Science\/Nature NASA's On Alert For Big Scary Asteroids. What About Smaller Ones? - NPR NASA\u2019s Tea Party Primary - In The Loop Assets and Liabilities - Space KSC\u00a0-\u2026","rel":"","context":"In &quot;Space Policy&quot;","block_context":{"text":"Space Policy","link":"https:\/\/hobbyspace.com\/Blog\/?cat=7"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":26019,"url":"https:\/\/hobbyspace.com\/Blog\/?p=26019","url_meta":{"origin":10872,"position":3},"title":"Videos: \u201cSpace to Ground\u201d &#038; other space habitat reports \u2013 July.17.2023","author":"TopSpacer","date":"July 17, 2023","format":false,"excerpt":"Here is the latest episode in NASA's Space to Ground weekly report on activities related to the International Space Station: https:\/\/youtu.be\/uLDKheI-g98 ** Expedition 69 Astronaut Frank Rubio Talks with the Congressional Hispanic Caucus - July 13, 2023 -\u00a0NASA Video Expedition 69 Flight Engineer Frank Rubio of NASA discussed life and\u2026","rel":"","context":"In &quot;In Space Infrastructure&quot;","block_context":{"text":"In Space Infrastructure","link":"https:\/\/hobbyspace.com\/Blog\/?cat=15"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/hobbyspace.com\/Blog\/wp-content\/uploads\/2023\/07\/1200px-International_Space_Station_after_undocking_of_STS-132-500x319.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":26076,"url":"https:\/\/hobbyspace.com\/Blog\/?p=26076","url_meta":{"origin":10872,"position":4},"title":"Videos: \u201cSpace to Ground\u201d &#038; other space habitat reports \u2013 Aug.15.2023","author":"TopSpacer","date":"August 15, 2023","format":false,"excerpt":"Here is this week's selection of videos about space stations and living in space starting with NASA's latest Space to Ground report for the International Space Station: https:\/\/youtu.be\/3sDX2laa5bo ** Expedition 69 Astronaut Frank Rubio Talks with ABC\u2019s Good Morning America - Aug. 11, 2023 - NASA Video Aboard the International\u2026","rel":"","context":"In &quot;In Space Infrastructure&quot;","block_context":{"text":"In Space Infrastructure","link":"https:\/\/hobbyspace.com\/Blog\/?cat=15"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/hobbyspace.com\/Blog\/wp-content\/uploads\/2023\/07\/1200px-International_Space_Station_after_undocking_of_STS-132-500x319.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]},{"id":25878,"url":"https:\/\/hobbyspace.com\/Blog\/?p=25878","url_meta":{"origin":10872,"position":5},"title":"Videos: \u201cSpace to Ground\u201d &#038; other space habitat reports \u2013 May.2.2023","author":"TopSpacer","date":"May 2, 2023","format":false,"excerpt":"Here is the latest episode in NASA's Space to Ground weekly report on activities related to the International Space Station: https:\/\/youtu.be\/LuPWd5jGsEM ** Canadarm dance | 4K timelapse -\u00a0European Space Agency, ESA Timelapse video made during ESA astronaut Thomas Pesquet\u2019s second mission to the International Space Station, \u201cAlpha\u201d. 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